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Comparing Treatment Options

  The VNUS® Closure® Procedure* Endovenous Laser Vein Stripping & Ligation
Typical results 48 hours after procedure
Method of action Collagen contraction resulting in a fibrotic seal1 Boiling of blood resulting in a thrombotic occlusion2 Surgical removal
Multi-center registry 97.4% closure at 1 year3 None No multi-center studies
Post-operative bruising 4%4

Return to normal activities withing 24 hours 89.1% of patients6
80.5% of patients5
69.8% of patients6
46.9% of patients5

* These results were obtained using the VNUS Closure® and ClosurePLUS™ RF products with expandable electrodes.

1. Pichot O, et al. Role of duplex imaging in endovenous obliteration for primary venous insufficiency. J Endovasc Ther. 2000;7:451-9.
2. Proebstle TM, et al. Endovenous treatment of the greater saphenous vein with a 940 nm diode laser: thrombotic occlusion after endoluminal thermal damage by laser generated steam bubbles. J Vasc Surg. 2002;35:729-736.
3. Dietzek A, Two-Year Follow-Up Data From A Prospective, Multicenter Study Of The Efficacy Of The ClosureFAST Catheter, 35th Annual Veith Symposium. November 19, 2008. New York.
4. Morrison, N. Poster presented at American Venous Forum Meeting, February 2003.
5. Lurie F, et al. Prospective Randomized Study of Endovenous Radiofrequency Obliteration (Closure) Versus Ligation and Vein Stripping (EVOLVeS). J Vasc Surg. 2003;38:207-14.
6. Morrison N. Presented at the Union Internationale de Phlebologie, Rome, September 2001.

Safety Summary

As with any medical intervention, potential risks and complications exist with the Closure procedure. Please consult Dr Ly to receive further information.

The Closure System is intended for endovascular coagulation of blood vessels in patients with superficial venous reflux. It is contraindicated in patients with thrombus in the vein segment to be treated.

Potential complications include, but are not limited to, vessel perforation, thrombosis, pulmonary embolism, phlebitis, hematoma, infection, paresthesia, skin burn.

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